Home » Yescarta® Sets a New Benchmark: Powerful, Durable Results for Even the Toughest-to-Treat Lymphoma Patients

Yescarta® Sets a New Benchmark: Powerful, Durable Results for Even the Toughest-to-Treat Lymphoma Patients

by admin477351

At ASH 2025, Kite unveiled data that underscores a clear message: Yescarta® is reshaping expectations for relapsed or refractory large B-cell lymphoma.

By combining long-term results from ZUMA-7 and ALYCANTE, researchers showed that Yescarta delivers remarkably consistent survival and response rates—including for patients once considered too high-risk for transplant or aggressive chemotherapy.

Breakthrough results at two years:
Nearly 65% survival — tripling historical outcomes
Strong, lasting disease control across both studies
Over 55% complete responses within three months
More than 60% of responders staying in response for a year

Safety remained stable and predictable, with comparable rates of serious side effects in both trials.
Patients also saw meaningful quality-of-life improvements that strengthened over time.

Experts emphasize that these findings reinforce Yescarta’s role as a therapy with curative intent and a transformative option for patients with aggressive lymphoma.

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